Hiroshi Yamashita Selected Research

lycoctonine

9/2022

Bioactivity inspired C19-diterpenoid alkaloids for overcoming multidrug-resistant cancer.

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Hiroshi Yamashita Research Topics

Disease

11	Neoplasms (Cancer) 09/2022 - 09/2004
8	Parkinson Disease (Parkinson's Disease) 11/2008 - 03/2002
6	Insulin Resistance 09/2020 - 01/2002
5	Disease Progression 02/2021 - 01/2006
5	Seizures (Absence Seizure) 01/2019 - 07/2003
5	Infections 01/2019 - 10/2007
5	Noise-Induced Hearing Loss (Acoustic Trauma) 09/2014 - 01/2004
4	Brain Neoplasms (Brain Tumor) 01/2022 - 11/2012
4	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 02/2020 - 06/2006
4	Hearing Loss (Hearing Impairment) 10/2019 - 05/2008
4	Gestational Diabetes (Gestational Diabetes Mellitus) 02/2018 - 01/2002
4	Wounds and Injuries (Trauma) 01/2018 - 01/2004
4	Obesity 01/2017 - 06/2007
3	Gastroesophageal Reflux (GERD) 01/2022 - 01/2015
3	Peptic Esophagitis (Reflux Esophagitis) 01/2022 - 01/2017
3	Non-Erosive Reflux Disease 01/2022 - 01/2012
3	Necrosis 12/2021 - 11/2012
3	Sensorineural Hearing Loss 02/2021 - 01/2017
3	Breast Neoplasms (Breast Cancer) 06/2019 - 02/2011
3	Liver Diseases (Liver Disease) 01/2015 - 09/2003
3	Mental Disorders (Mental Disorder) 09/2014 - 01/2003
3	Fever (Fevers) 10/2007 - 09/2003
3	Hypoxia (Hypoxemia) 02/2007 - 10/2004
3	Ischemia 11/2006 - 11/2002
3	Squamous Cell Carcinoma of Head and Neck 05/2006 - 07/2004
3	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2003 - 11/2002
2	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 02/2021 - 01/2016
2	Hemorrhage 04/2020 - 11/2010
2	Body Weight (Weight, Body) 10/2019 - 11/2016
2	Triple Negative Breast Neoplasms 09/2019 - 06/2019
2	Carcinoma (Carcinomatosis) 06/2019 - 11/2003
2	Deafness (Deaf Mutism) 03/2019 - 01/2017
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 12/2012
2	Hematoma 01/2019 - 02/2016
2	Diabetes Mellitus 01/2019 - 03/2003
2	Nasopharyngeal Neoplasms (Cancer of the Nasopharynx) 04/2018 - 01/2018
2	Heart Failure 01/2018 - 01/2017
2	Chronic Renal Insufficiency 09/2017 - 01/2013
2	Abscess 01/2017 - 05/2007
2	Proteinuria 01/2015 - 01/2013
2	Neoplasm Metastasis (Metastasis) 01/2014 - 12/2009
2	Aneurysm (Aneurysms) 01/2014 - 05/2006
2	Inflammation (Inflammations) 11/2013 - 04/2011
2	Ventricular Tachycardia 09/2013 - 08/2010
2	Ulcer 11/2010 - 12/2005
2	Vertigo (Positional Vertigo) 06/2006 - 04/2004
2	Meniere Disease (Menieres Disease) 06/2006 - 04/2004

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 02/2011 - 06/2002
6	Glucose (Dextrose)FDA LinkGeneric 09/2020 - 03/2003
6	Proton Pump InhibitorsIBA 01/2019 - 11/2010
5	2- (N- (4- chlorophenyl)- N- methylamino)- 4H- pyrido(3,2- e)- 1,3- thiazin- 4- oneIBA 01/2019 - 07/2003
5	Pharmaceutical PreparationsIBA 09/2014 - 07/2003
5	UbiquitinIBA 08/2008 - 11/2003
5	alpha-SynucleinIBA 08/2006 - 05/2002
4	Insulin (Novolin)FDA Link 09/2020 - 03/2003
4	SteroidsIBA 01/2017 - 01/2014
4	EdaravoneIBA 10/2005 - 03/2003
4	Anticonvulsants (Antiepileptic Drugs)IBA 08/2004 - 07/2003
3	AlkaloidsIBA 09/2022 - 01/2018
3	1- (5- (2- fluorophenyl)- 1- (pyridin- 3- ylsulfonyl)- 1H- pyrrol- 3- yl)- N- methylmethanamineIBA 01/2022 - 01/2017
3	AcidsIBA 01/2022 - 01/2012
3	Vincristine (Oncovin)FDA LinkGeneric 01/2022 - 01/2018
3	Silver Sulfadiazine (SSD)FDA LinkGeneric 01/2022 - 03/2021
3	PotassiumIBA 01/2022 - 01/2017
3	Methylprednisolone FDA LinkGeneric 12/2018 - 09/2003
3	Therapeutic UsesIBA 07/2014 - 03/2002
3	Heat-Shock Proteins (Heat-Shock Protein)IBA 05/2008 - 11/2003
3	Diazepam (Valium)FDA LinkGeneric 06/2006 - 01/2004
3	DNA (Deoxyribonucleic Acid)IBA 05/2006 - 07/2004
3	AMPA Receptors (AMPA Receptor)IBA 08/2004 - 07/2003
3	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 06/2004 - 07/2003
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 09/2022 - 09/2019
2	C-Reactive ProteinIBA 03/2022 - 08/2009
2	Blood Glucose (Blood Sugar)IBA 10/2019 - 11/2016
2	DiterpenesIBA 06/2019 - 01/2018
2	CytokinesIBA 03/2019 - 09/2003
2	Z 338IBA 01/2019 - 01/2015
2	Neomycin FDA LinkGeneric 01/2018 - 05/2015
2	Adrenal Cortex Hormones (Corticosteroids)IBA 03/2017 - 01/2014
2	Indicators and Reagents (Reagents)IBA 01/2017 - 01/2006
2	Peroxidase (Myeloperoxidase)IBA 01/2016 - 01/2015
2	Substance PIBA 05/2015 - 09/2014
2	EnzymesIBA 12/2014 - 11/2003
2	Dopamine (Intropin)FDA LinkGeneric 09/2014 - 06/2006
2	LuciferasesIBA 01/2014 - 12/2009
2	Immunoglobulin G (IgG)IBA 01/2014 - 04/2009
2	Biomarkers (Surrogate Marker)IBA 01/2014 - 12/2009
2	Cyclosporine (Ciclosporin)FDA LinkGeneric 09/2013 - 09/2003
2	AntibodiesIBA 06/2013 - 06/2007
2	Lapatinib (GW572016)FDA Link 11/2012 - 12/2009
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2012 - 06/2007
2	Prednisolone (Predate)FDA LinkGeneric 01/2012 - 09/2003
2	Small Interfering RNA (siRNA)IBA 06/2010 - 11/2006
2	geranylgeranylacetone (teprenone)IBA 05/2008 - 12/2005
2	Proteasome Endopeptidase Complex (Proteasome)IBA 07/2007 - 11/2003

Therapy/Procedure

15	Therapeutics 03/2019 - 01/2003
5	Renal Dialysis (Hemodialysis) 05/2019 - 01/2010
3	Oral Administration 10/2019 - 07/2003
2	Cardiac Resynchronization Therapy 01/2018 - 01/2017
2	Blood Component Removal (Apheresis) 07/2014 - 11/2013